A truck driver has died and five people have been taken to hospital after a horrific crash on the Hume Freeway in northeastern Victoria.

Emergency services rushed to the major freeway near Harrys Creek Road in Violet Town, about 174km from Melbourne, just before 1.30pm on Friday.

Police had received a report that a B-double truck had been involved in a collision.

It is believed the truck collided with a road worker’s truck before veering across the median strip, police said.

The vehicle allegedly clipped a car, before it rolled and caught fire – with footage of the scene showing the vehicle on its side.

The driver of the B-double truck, who is yet to be formally identified, died at the scene.

The driver of the second truck, believed to be in his 50s, was transported to hospital with non-life-threatening injuries.

Two adults and two children inside the clipped car were also taken to hospital for observation.

A truck driver has died and five people have been taken to hospital after a horrific crash on the Hume Freeway in Violent Town, in northeastern Victoria

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The CFA issued a warning for a hazardous liquid spill in the area surrounding the crash

The crash was attended by the Country Fire Authority (CFA), Victoria Police, State Emergency Service, Fire Rescue Victoria, and Ambulance Victoria.

The CFA issued a warning for a hazardous liquid spill in the area surrounding the crash, ABC News reported.

However, authorities assured locals there was no threat to the community.

Victoria Police said the circumstances surrounding the collision are yet to be established. An investigation is ongoing.

Anyone who witnessed the incident or has footage or information is urged to contact Crime Stoppers on 1800 333 000.

There have been 72 lives lost on roads in Victoria so far this year, down from 87 deaths at the same time in 2025.