Homicide detectives arrived to search the area after a man was arrested over the death of a man and woman in a horrific Quakers Hill stabbing. Picture: NewsWire / Christian Gilles

A man has been charged with the murder of two people who were found stabbed to death in northwest Sydney in the early hours of Sunday morning.

Just before 5am, emergency services were called to a home on Illabo Street, Quakers Hill, after neighbours called police reporting a loud disturbance.

Officers arrived to find a critically injured man, aged 30, on the footpath in front of the property and a 38-year-old woman dead inside the kitchen of the home.

Both were located with multiple stab wounds.

Police have establish a crime scene as investigations into the double stabbing continue. Picture: NewsWire / Christian Gilles

The female victim has been identified as 38-year-old Anaseini Waqavuki. Picture: Facebook

The female victim has been identified as Anaseini Waqavuki and was being mourned by the Fijian community on social media.

The injured man was treated by NSW Ambulance paramedics and taken to Liverpool Hospital in a critical condition.

He died about 9am, according to NSW Police.

A 47-year-old man, who is known to police, was arrested after attending Blacktown Police Station at about 5.30am.

He has since been charged with two counts of murder.

The man was refused bail and is expected to face court on Monday.

Police and detectives remains at the crime scene. Picture: NewsWire / Christian Gilles

Addressing media on Sunday, NSW Police Superintendent Jason Joyce said the incident appeared to be domestic violence-related.

“We believe that the deceased female and deceased male were in a relationship,” he said.

“The male that’s in custody was previously in a relationship with the female.”

Police have established crime scenes the Quakers Hill residence, a service station on Richmond Road in Woodcroft where a knife was recovered and the residence of the male currently in custody.

Superintendent Joyce said emergency services and neighbours were faced with “traumatic” and “confronting” scenes, with both victims sustaining multiple stab wounds.

A neighbour told Nine News he heard about four “wordless screams of fear” followed by dogs barking and then “pure silence” until police arrived.

Crime scene investigators were seen at the home on Sunday. Picture: NewsWire / Christian Gilles

The officer stressed the investigation was in its infancy and called for anyone with information or CCTV to come forward.

“At this stage we’re just aware that the male and female deceased were at that location when the incident occurred … the person who’s currently in custody arrived at some point during the night,” he said.

Shocked neighbours described hearing a commotion about 4.30am on Sunday.

“There was a couple of brief crashes … and then a lady screamed,” one resident told the ABC.

Police have urged any witnesses or anyone with CCTV or dashcam footage between 4.30am and 5.30am to contact Crime Stoppers on 1800 333 000.