San Francisco 49ers practice squad offensive lineman Isaac Alarcon has been suspended for the first six games of the upcoming season for violating the NFL’s policy on performance-enhancing substances.

The league announced the suspension on Wednesday.

Alarcon will be able to participate in the offseason program, training camp and exhibitions before the suspension starts.

Alarcon has never played in a regular-season game since entering the league out of Mexico as part of the international pathway program with Dallas in 2020.

Alarcon spent last season on the practice squad for the 49ers after playing 43 snaps in the preseason.

He was re-signed earlier this offseason by San Francisco.

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San Francisco 49ers offensive lineman Isaac Alarcon has been suspended for six games

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Alarcon entered the NFL out of Mexico as part of the international pathway program with Dallas

it is the latest issue to engulf the 49ers in a busy offseason as they try to bounce back from a disappointing season.

It was announced last month that wide receiver Brandon Aiyuk is expected to remain with the team, granting him a $22.85million bonus.

The 49ers traded wide receiver Deebo Samuel to the Washington Commanders on March 1 in exchange for a fifth-round draft pick.

Aiyuk, 27, recorded 25 catches for 374 yards and no touchdowns in seven games before his season ended after sustaining an ACL and MCL injury in his right knee against the Kansas City Chiefs on October 20.

A second-team All-Pro selection in 2023, Aiyuk staged an offseason holdout before accepting a four-year, $120m contract extension in late August.

Aiyuk has 294 receptions for 4,305 yards and 25 touchdowns in 69 career games since the 49ers selected him with the 25th overall pick of the 2020 NFL Draft.